Science history is chock full of world-changing innovations that initially faced skepticism and ridicule for being too unconventional: light bulbs, cars, and home computers are just a few examples. In this audiobook, we take a look at the latest out-of-the-box ideas to tackle today’s biggest challenges, including so-called sponge cities designed to combat flooding, technology that mimics photosynthesis to produce fuel, modifying bacteria’s genetic circuits to treat genetic diseases, and much more.