Oregon, 1851. Eli and Charlie Sisters, notorious professional killers, are on their way to California to kill a man named Hermann Kermit Warm. On the way, the brothers have a series of unsettling experiences in the landscape of Gold Rush America. And they bicker a lot. Arriving in California, and discover that Warm has invented a magical formula, which could make all of them very rich. What happens next is utterly gripping, strange and sad....