In a world teetering on the brink of collapse, a group of survivors learns the cost of survival - and the value of fighting for something even after losing everything.

A mysterious virus suddenly strikes down millions. Three days later, its victims awake with a single purpose: spread the Infection. As the world lurches toward the apocalypse, some of the infected continue to change, transforming into horrific monsters.

In one American city, a small group struggles to survive. Sarge, a tank commander hardened by years of fighting in Afghanistan. Wendy, a cop still fighting for law and order in a lawless land. Ethan, a teacher searching for his lost family. Todd, a high school student who sees second chances in the end of the world. Paul, a minister who wonders why God has forsaken his children. And Anne, their mysterious leader, who holds an almost fanatical hatred for the infected.

Together, they fight their way to a massive refugee camp where thousands have made a stand. There, what's left of the government will ask them to accept a mission that will determine the survival of them all - a dangerous journey back onto the open road, and into the very heart of Infection.