Paul, Apostle of Christ is the story of two men. Luke, as a friend and physician, risks his life every time he ventures into the city of Rome to visit Paul, held captive in Nero's bleakest prison cell. Before Paul's execution, Luke resolves to write another book, one that details the beginnings of "The Way" and the birth of what will come to be known as the church. But Nero is determined to rid Rome of Christians.